Oral delivery of carrier-free dual-drug nanocrystal self-assembled microspheres improved NAD(+) bioavailability and attenuated cardiac ischemia/reperfusion injury in mice

Nicotinamide riboside (NR), as a dietary supplement, can be converted to nicotinamide adenine dinucleotide (NAD(+)) in cells to support mitochondrial energy metabolism. However, the efficacy of oral administrated NR is limited due to its quick degradation in circulation and low bioavailability in ta...

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Detalles Bibliográficos
Autores principales: Nie, Hongfei, Zhang, Yarong, Yu, Haiyang, Xiao, Hong, Li, Tao, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899691/
https://www.ncbi.nlm.nih.gov/pubmed/33605178
http://dx.doi.org/10.1080/10717544.2021.1886198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899691/
https://www.ncbi.nlm.nih.gov/pubmed/33605178
http://dx.doi.org/10.1080/10717544.2021.1886198

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