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Ca(2+)-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide

Cell penetration after recognition of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane with cellular membranes are the early steps of infectivity. A region of the Spike protein of the virus, identified as the “f...

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Detalles Bibliográficos
Autores principales: Khelashvili, George, Plante, Ambrose, Doktorova, Milka, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899928/
https://www.ncbi.nlm.nih.gov/pubmed/33631204
http://dx.doi.org/10.1016/j.bpj.2021.02.023