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Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel

Triple-negative breast cancer (TNBC) patients exhibit variable responses to chemotherapy, suggesting an underlying molecular heterogeneity. In the current study, we analyzed publicly available transcriptome data from 360 TNBC and 88 normal breast tissues, which revealed activation of nucleosome and...

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Detalles Bibliográficos
Autores principales: Elango, Ramesh, Vishnubalaji, Radhakrishnan, Shaath, Hibah, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899947/
https://www.ncbi.nlm.nih.gov/pubmed/33665229
http://dx.doi.org/10.1016/j.omtm.2021.01.013