Cargando…
Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel
Triple-negative breast cancer (TNBC) patients exhibit variable responses to chemotherapy, suggesting an underlying molecular heterogeneity. In the current study, we analyzed publicly available transcriptome data from 360 TNBC and 88 normal breast tissues, which revealed activation of nucleosome and...
Autores principales: | Elango, Ramesh, Vishnubalaji, Radhakrishnan, Shaath, Hibah, Alajez, Nehad M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899947/ https://www.ncbi.nlm.nih.gov/pubmed/33665229 http://dx.doi.org/10.1016/j.omtm.2021.01.013 |
Ejemplares similares
-
Therapeutic targeting of the TPX2/TTK network in colorectal cancer
por: Shaath, Hibah, et al.
Publicado: (2023) -
Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy
por: Shaath, Hibah, et al.
Publicado: (2021) -
Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
por: Elango, Ramesh, et al.
Publicado: (2021) -
Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2020) -
Long non-coding RNA (lncRNA) transcriptional landscape in breast cancer identifies LINC01614 as non-favorable prognostic biomarker regulated by TGFβ and focal adhesion kinase (FAK) signaling
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2019)