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Digital PCR for high sensitivity viral detection in false-negative SARS-CoV-2 patients

Patients requiring diagnostic testing for coronavirus disease 2019 (COVID-19) are routinely assessed by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) amplification of Sars-CoV-2 virus RNA extracted from oro/nasopharyngeal swabs. Despite the good specificity of the assays cer...

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Detalles Bibliográficos
Autores principales: Poggio, Paolo, Songia, Paola, Vavassori, Chiara, Ricci, Veronica, Banfi, Cristina, Barbieri, Silvia Stella, Garoffolo, Gloria, Myasoedova, Veronika A., Piacentini, Luca, Raucci, Angela, Scopece, Alessandro, Sommariva, Elena, Vinci, Maria Cristina, Carcione, Davide, Biondi, Maria Luisa, Mancini, Maria Elisabetta, Formenti, Alberto, Andreini, Daniele, Assanelli, Emilio M., Agostoni, Piergiuseppe, Camera, Marina, Colombo, Gualtiero I., Pesce, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900100/
https://www.ncbi.nlm.nih.gov/pubmed/33619321
http://dx.doi.org/10.1038/s41598-021-83723-x