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Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients

Hospitalized COVID-19 patients often present with a large spectrum of clinical symptoms. There is a critical need to better understand the immune responses to SARS-CoV-2 that lead to either resolution or exacerbation of the clinical disease. Here, we examine longitudinal plasma samples from hospital...

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Detalles Bibliográficos
Autores principales: Tang, Juanjie, Ravichandran, Supriya, Lee, Youri, Grubbs, Gabrielle, Coyle, Elizabeth M., Klenow, Laura, Genser, Hollie, Golding, Hana, Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900119/
https://www.ncbi.nlm.nih.gov/pubmed/33619281
http://dx.doi.org/10.1038/s41467-021-21463-2