Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a disorder of accelerated lung aging. Multiple pieces of evidence support that the aging biomarker short telomeres, which can be caused by mutations in telomerase reverse transcriptase (TERT), contribute to COPD pathogenesis. We hypothesized that short...

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Detalles Bibliográficos
Autores principales: Xu, Jialin, de Oliveira, Diego Madureira, Trudeau, Matthew A., Yang, Yang, Chin, Jessica J. Y., Sin, Don D., Sandford, Andrew J., Wong, Judy M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900122/
https://www.ncbi.nlm.nih.gov/pubmed/33619289
http://dx.doi.org/10.1038/s41598-021-83686-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900122/
https://www.ncbi.nlm.nih.gov/pubmed/33619289
http://dx.doi.org/10.1038/s41598-021-83686-z

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