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Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions

Diseases of the bile duct (cholangiopathies) remain a common indication for liver transplantation, while little progress has been made over the last decade in understanding the underlying pathophysiology. This is largely due to lack of proper in vitro model systems to study cholangiopathies. Recentl...

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Detalles Bibliográficos
Autores principales: Roos, Floris J. M., Verstegen, Monique M. A., Muñoz Albarinos, Laura, Roest, Henk P., Poley, Jan-Werner, Tetteroo, Geert W. M., IJzermans, Jan N. M., van der Laan, Luc J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900156/
https://www.ncbi.nlm.nih.gov/pubmed/33634107
http://dx.doi.org/10.3389/fcell.2020.630492