Cargando…
Human Bile Contains Cholangiocyte Organoid-Initiating Cells Which Expand as Functional Cholangiocytes in Non-canonical Wnt Stimulating Conditions
Diseases of the bile duct (cholangiopathies) remain a common indication for liver transplantation, while little progress has been made over the last decade in understanding the underlying pathophysiology. This is largely due to lack of proper in vitro model systems to study cholangiopathies. Recentl...
Autores principales: | Roos, Floris J. M., Verstegen, Monique M. A., Muñoz Albarinos, Laura, Roest, Henk P., Poley, Jan-Werner, Tetteroo, Geert W. M., IJzermans, Jan N. M., van der Laan, Luc J. W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900156/ https://www.ncbi.nlm.nih.gov/pubmed/33634107 http://dx.doi.org/10.3389/fcell.2020.630492 |
Ejemplares similares
-
Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro
por: Roos, Floris J. M., et al.
Publicado: (2021) -
Bile Duct Repair in Human Liver Grafts: Effective Cholangiocyte Organoid Engraftment and Plasticity
por: van der Laan, Luc J.W., et al.
Publicado: (2021) -
Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids
por: Shi, Shaojun, et al.
Publicado: (2021) -
Protocol for inducing branching morphogenesis in human cholangiocyte and cholangiocarcinoma organoids
por: Ober, Kimberley, et al.
Publicado: (2023) -
Modeling bile duct ischemia and reoxygenation injury in human cholangiocyte organoids for screening of novel cholangio-protective agents
por: Shi, Shaojun, et al.
Publicado: (2023)