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Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodrome

An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to intervening in disease course. We developed an animal model—Enhance...

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Detalles Bibliográficos
Autores principales: Petty, Alice, Cui, Xiaoying, Ali, Asad, Du, Zilong, Srivastav, Sunil, Kesby, James P., Kirik, Deniz, Howes, Oliver, Eyles, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900200/
https://www.ncbi.nlm.nih.gov/pubmed/33619296
http://dx.doi.org/10.1038/s41598-021-83681-4