Complex biology of constitutional ring chromosomes structure and (in)stability revealed by somatic cell reprogramming

Human ring chromosomes are often unstable during mitosis, and daughter cells can be partially or completely aneuploid. We studied the mitotic stability of four ring chromosomes, 8, 13, 18, and 22, in long-term cultures of skin fibroblasts and induced pluripotent stem cells (iPSCs) by GTG karyotyping...

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Detalles Bibliográficos
Autores principales: Nikitina, T. V., Kashevarova, A. A., Gridina, M. M., Lopatkina, M. E., Khabarova, A. A., Yakovleva, Yu. S., Menzorov, A. G., Minina, Yu. A., Pristyazhnyuk, I. E., Vasilyev, S. A., Fedotov, D. A., Serov, O. L., Lebedev, I. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900208/
https://www.ncbi.nlm.nih.gov/pubmed/33619287
http://dx.doi.org/10.1038/s41598-021-83399-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900208/
https://www.ncbi.nlm.nih.gov/pubmed/33619287
http://dx.doi.org/10.1038/s41598-021-83399-3

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