Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints

Broad evidence in the literature supports double-strand breaks (DSBs) as initiators of mitochondrial DNA (mtDNA) deletion mutations. While DNA misalignment during DSB repair is commonly proposed as the mechanism by which DSBs cause deletion mutations, details such as the specific DNA repair errors a...

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Detalles Bibliográficos
Autores principales: Lakshmanan, Lakshmi Narayanan, Yee, Zhuangli, Halliwell, Barry, Gruber, Jan, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900216/
https://www.ncbi.nlm.nih.gov/pubmed/33665557
http://dx.doi.org/10.1016/j.isci.2021.102138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900216/
https://www.ncbi.nlm.nih.gov/pubmed/33665557
http://dx.doi.org/10.1016/j.isci.2021.102138

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