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Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints
Broad evidence in the literature supports double-strand breaks (DSBs) as initiators of mitochondrial DNA (mtDNA) deletion mutations. While DNA misalignment during DSB repair is commonly proposed as the mechanism by which DSBs cause deletion mutations, details such as the specific DNA repair errors a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900216/ https://www.ncbi.nlm.nih.gov/pubmed/33665557 http://dx.doi.org/10.1016/j.isci.2021.102138 |