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Contributions of biliary epithelial cells to hepatocyte homeostasis and regeneration in zebrafish

Whether transdifferentiation of the biliary epithelial cells (BECs) to hepatocytes occurs under physiological conditions and contributes to liver homeostasis remains under long-term debate. Similar questions have been raised under pathological circumstances if a fibrotic liver is suffered from sever...

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Detalles Bibliográficos
Autores principales: Zhang, Wenfeng, Chen, Jingying, Ni, Rui, Yang, Qifen, Luo, Lingfei, He, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900353/
https://www.ncbi.nlm.nih.gov/pubmed/33665561
http://dx.doi.org/10.1016/j.isci.2021.102142