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A computational framework of host-based drug repositioning for broad-spectrum antivirals against RNA viruses

RNA viruses are responsible for many zoonotic diseases that post great challenges for public health. Effective therapeutics against these viral infections remain limited. Here, we deployed a computational framework for host-based drug repositioning to predict potential antiviral drugs from 2,352 app...

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Detalles Bibliográficos
Autores principales: Li, Zexu, Yao, Yingjia, Cheng, Xiaolong, Chen, Qing, Zhao, Wenchang, Ma, Shixin, Li, Zihan, Zhou, Hu, Li, Wei, Fei, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900436/
https://www.ncbi.nlm.nih.gov/pubmed/33665567
http://dx.doi.org/10.1016/j.isci.2021.102148