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GSK3 inhibitor ameliorates steatosis through the modulation of mitochondrial dysfunction in hepatocytes of obese patients

Obesity is an important risk factor and a potential treatment target for hepatic steatosis. The maladaptation of hepatic mitochondrial flexibility plays a key role in the hepatic steatosis. Herein, we found that hepatocyte-like cells derived from human adipose stem cell of obese patients exhibited t...

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Detalles Bibliográficos
Autores principales: Li, Yaqiong, Lin, Yi, Han, Xueya, Li, Weihong, Yan, Wenmao, Ma, Yuejiao, Lu, Xin, Huang, Xiaowu, Bai, Rixing, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900441/
https://www.ncbi.nlm.nih.gov/pubmed/33665568
http://dx.doi.org/10.1016/j.isci.2021.102149