Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M

As transcription and replication use DNA as substrate, conflicts between transcription and replication can occur, leading to genome instability with direct consequences for human health. To determine how the two processes are coordinated throughout S phase, we characterize both processes together at...

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Detalles Bibliográficos
Autores principales: Wang, Jianming, Rojas, Patricia, Mao, Jingwen, Mustè Sadurnì, Martina, Garnier, Olivia, Xiao, Songshu, Higgs, Martin R., Garcia, Paloma, Saponaro, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900609/
https://www.ncbi.nlm.nih.gov/pubmed/33596418
http://dx.doi.org/10.1016/j.celrep.2021.108759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900609/
https://www.ncbi.nlm.nih.gov/pubmed/33596418
http://dx.doi.org/10.1016/j.celrep.2021.108759

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