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Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M
As transcription and replication use DNA as substrate, conflicts between transcription and replication can occur, leading to genome instability with direct consequences for human health. To determine how the two processes are coordinated throughout S phase, we characterize both processes together at...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900609/ https://www.ncbi.nlm.nih.gov/pubmed/33596418 http://dx.doi.org/10.1016/j.celrep.2021.108759 |