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Oncolytic vaccinia virus induces a novel phenotype of CD8(+) effector T cells characterized by high ICOS expression

Characterization of the intratumoral immune status is important for developing immunotherapies and evaluating their antitumor effectiveness. CD8(+) T cells are one of the most important cell types that directly and indirectly contribute to antitumor efficacy by releasing cytolytic molecules and infl...

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Detalles Bibliográficos
Autores principales: Yamashita, Midori, Tasaki, Mamoru, Murakami, Ryuji, Arai, Yukinori, Nakamura, Takafumi, Nakao, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900640/
https://www.ncbi.nlm.nih.gov/pubmed/33665362
http://dx.doi.org/10.1016/j.omto.2021.01.016