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Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species

BACKGROUND AND AIM: Acute myeloid leukemia (AML), initiated and maintained by leukemia stem cells (LSCs), is often relapsed or refractory to therapy. The present study aimed at assessing the effects of nanozyme-like Fe(3)O(4) nanoparticles (IONPs) combined with cytosine arabinoside (Ara-C) on LSCs i...

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Detalles Bibliográficos
Autores principales: Dou, Jun, Li, Luoyang, Guo, Mei, Mei, Feng, Zheng, Danfeng, Xu, Hui, Xue, Rui, Bao, Xueyang, Zhao, Fengshu, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900778/
https://www.ncbi.nlm.nih.gov/pubmed/33633448
http://dx.doi.org/10.2147/IJN.S278885