A “Target Class” Screen to Identify Activators of Two-Pore Domain Potassium (K2P) Channels

Two-pore domain potassium (K2P) channels carry background (or leak) potassium current and play a key role in regulating resting membrane potential and cellular excitability. Accumulating evidence points to a role for K2Ps in human pathophysiologies, most notably in pain and migraine, making them att...

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Detalles Bibliográficos
Autores principales: McCoull, David, Ococks, Emma, Large, Jonathan M., Tickle, David C., Mathie, Alistair, Jerman, Jeffrey, Wright, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900820/
https://www.ncbi.nlm.nih.gov/pubmed/33375888
http://dx.doi.org/10.1177/2472555220976126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900820/
https://www.ncbi.nlm.nih.gov/pubmed/33375888
http://dx.doi.org/10.1177/2472555220976126

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