Knockdown of Claudin-19 in the Retinal Pigment Epithelium Is Accompanied by Slowed Phagocytosis and Increased Expression of SQSTM1

PURPOSE: Besides regulating paracellular diffusion, claudin-19 modulates the expression of proteins essential for the retinal pigment epithelium (RPE). This study asks how RPE responds when the expression of claudin-19 is reduced. METHODS: In stem cell-derived RPE, claudin-19 and sequestosome-1/p62...

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Detalles Bibliográficos
Autores principales: Liu, Fanfei, Peng, Shaomin, Adelman, Ron A., Rizzolo, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900869/
https://www.ncbi.nlm.nih.gov/pubmed/33591357
http://dx.doi.org/10.1167/iovs.62.2.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900869/
https://www.ncbi.nlm.nih.gov/pubmed/33591357
http://dx.doi.org/10.1167/iovs.62.2.14

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