Hypoxia Induces Galectin-1 Expression Via Autoinduction of Placental Growth Factor in Retinal Pigment Epithelium Cells

PURPOSE: Galectin-1/LGALS1, a β-galactoside-binding protein, contributes to angiogenesis and fibrosis in various ocular diseases. Hypoxia-dependent and -independent pathways upregulate galectin-1/LGALS1 expression in Müller glial cells. Here, we present novel findings on the galectin-1/LGALS1 regula...

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Detalles Bibliográficos
Autores principales: Yamamoto, Taku, Kanda, Atsuhiro, Kase, Satoru, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900883/
https://www.ncbi.nlm.nih.gov/pubmed/33599733
http://dx.doi.org/10.1167/iovs.62.2.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900883/
https://www.ncbi.nlm.nih.gov/pubmed/33599733
http://dx.doi.org/10.1167/iovs.62.2.22

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