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m(6)A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells

[Image: see text] N(6)-methyladenosine (m(6)A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m(6)A modification in RNA controls cellular proliferation and pluripotency and has been implicated in the progression of multiple disease...

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Detalles Bibliográficos
Autores principales: Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M., Wang, Yinsheng, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901021/
https://www.ncbi.nlm.nih.gov/pubmed/33412003
http://dx.doi.org/10.1021/acschembio.0c00841