The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation

BACKGROUND: NOTCH signaling has been shown to play a role in the production of interleukin-22 (IL-22) by CD4(+) T cells. Multiple T-helper (Th) cell populations secrete IL-22. Th22 (CD4(+)IL22(+)IFNγ(−)IL17A(−)) cells are a subgroup of CD4(+) effector T cells that primarily generate IL-22. The regul...

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Detalles Bibliográficos
Autores principales: Zeng, Chong, Shao, Zhongbao, Wei, Zibo, Yao, Jie, Wang, Weidong, Yin, Liang, YangOu, Huixian, Xiong, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901075/
https://www.ncbi.nlm.nih.gov/pubmed/33622250
http://dx.doi.org/10.1186/s11658-021-00249-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901075/
https://www.ncbi.nlm.nih.gov/pubmed/33622250
http://dx.doi.org/10.1186/s11658-021-00249-w

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