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Plasmatic and cell-based enhancement by microparticles originated from platelets and endothelial cells under simulated in vitro conditions of a dilutional coagulopathy

BACKGROUND: Aggressive fluid management and other external factors may lead to hypothermia, acidosis and hemodilution (defined as Lethal Triad, LT) contributing to a trauma-induced coagulopathy (TIC) that worsens patients’ outcomes. Procoagulant microparticles (MP) are crucial players at the interfa...

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Detalles Bibliográficos
Autores principales: Böhm, Julia K., Schäfer, Nadine, Maegele, Marc, Stümpges, Birgit, Bauerfeind, Ursula, Caspers, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901091/
https://www.ncbi.nlm.nih.gov/pubmed/33622398
http://dx.doi.org/10.1186/s13049-021-00847-9