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Suboptimal Discontinuous Current-Clamp Switching Rates Lead to Deceptive Mouse Neuronal Firing
Intracellular recordings using sharp microelectrodes often rely on a technique called discontinuous current-clamp (DCC) to accurately record the membrane potential while injecting current through the same microelectrode. It is well known that a poor choice of DCC switching rate can lead to underesti...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Society for Neuroscience
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901151/ https://www.ncbi.nlm.nih.gov/pubmed/33446514 http://dx.doi.org/10.1523/ENEURO.0461-20.2020 |