Downregulation of TTF1 in the rat hypothalamic ARC or AVPV nucleus inhibits Kiss1 and GnRH expression, leading to puberty delay

BACKGROUND: TTF1 is a transcription factor that is expressed in the hypothalamus after birth and plays crucial roles in pubertal development. TTF1 may regulate the expression of the Kiss1 gene, which may drive puberty onset in the hypothalamic arcuate (ARC) and anterior ventral paraventricular (AVPV...

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Detalles Bibliográficos
Autores principales: Zang, Shaolian, Yin, Xiaoqin, Li, Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901190/
https://www.ncbi.nlm.nih.gov/pubmed/33622350
http://dx.doi.org/10.1186/s12958-021-00710-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901190/
https://www.ncbi.nlm.nih.gov/pubmed/33622350
http://dx.doi.org/10.1186/s12958-021-00710-7

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