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T cells accumulate in non-diabetic islets during ageing

BACKGROUND: The resident immune population of pancreatic islets has roles in islet development, beta cell physiology, and the pathology of diabetes. These roles have largely been attributed to islet macrophages, comprising 90% of islet immune cells (in the absence of islet autoimmunity), and, in the...

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Detalles Bibliográficos
Autores principales: Denroche, Heather C., Miard, Stéphanie, Sallé-Lefort, Sandrine, Picard, Frédéric, Verchere, C. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901217/
https://www.ncbi.nlm.nih.gov/pubmed/33622333
http://dx.doi.org/10.1186/s12979-021-00221-4