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SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape

The 501Y.V2 variants of SARS-CoV-2 containing multiple mutations in spike are now dominant in South Africa and are rapidly spreading to other countries. Here, experiments with 18 pseudotyped viruses showed that the 501Y.V2 variants do not confer increased infectivity in multiple cell types except fo...

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Detalles Bibliográficos
Autores principales: Li, Qianqian, Nie, Jianhui, Wu, Jiajing, Zhang, Li, Ding, Ruxia, Wang, Haixin, Zhang, Yue, Li, Tao, Liu, Shuo, Zhang, Mengyi, Zhao, Chenyan, Liu, Huan, Nie, Lingling, Qin, Haiyang, Wang, Meng, Lu, Qiong, Li, Xiaoyu, Liu, Junkai, Liang, Haoyu, Shi, Yi, Shen, Yuelei, Xie, Liangzhi, Zhang, Linqi, Qu, Xiaowang, Xu, Wenbo, Huang, Weijin, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901273/
https://www.ncbi.nlm.nih.gov/pubmed/33735608
http://dx.doi.org/10.1016/j.cell.2021.02.042