Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta—Brief Report

OBJECTIVE: Efficient gene transfer to the vascular wall via intravenous vector injection would be useful for experimental vascular biology and gene therapy. Initial studies of lentiviral vector tropism suggested that intravenously injected vectors do not transduce murine vascular tissue; however, th...

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Detalles Bibliográficos
Autores principales: Bi, Lianxiang, Wacker, Bradley K., Stamatikos, Alexis, Sethuraman, Meena, Komandur, Kaushik, Dichek, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901533/
https://www.ncbi.nlm.nih.gov/pubmed/33297756
http://dx.doi.org/10.1161/ATVBAHA.120.315125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901533/
https://www.ncbi.nlm.nih.gov/pubmed/33297756
http://dx.doi.org/10.1161/ATVBAHA.120.315125

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