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Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta—Brief Report
OBJECTIVE: Efficient gene transfer to the vascular wall via intravenous vector injection would be useful for experimental vascular biology and gene therapy. Initial studies of lentiviral vector tropism suggested that intravenously injected vectors do not transduce murine vascular tissue; however, th...
Autores principales: | Bi, Lianxiang, Wacker, Bradley K., Stamatikos, Alexis, Sethuraman, Meena, Komandur, Kaushik, Dichek, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901533/ https://www.ncbi.nlm.nih.gov/pubmed/33297756 http://dx.doi.org/10.1161/ATVBAHA.120.315125 |
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