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Neural Progenitor Cell-Derived Extracellular Vesicles Enhance Blood-Brain Barrier Integrity by NF-κB (Nuclear Factor-κB)-Dependent Regulation of ABCB1 (ATP-Binding Cassette Transporter B1) in Stroke Mice

OBJECTIVE: Extracellular vesicles (EVs) derived from neural progenitor cells enhance poststroke neurological recovery, albeit the underlying mechanisms remain elusive. Since previous research described an enhanced poststroke integrity of the blood-brain barrier (BBB) upon systemic transplantation of...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Graf, Irina, Kuang, Yaoyun, Zheng, Xuan, Haupt, Matteo, Majid, Arshad, Kilic, Ertugrul, Hermann, Dirk M., Psychogios, Marios-Nikos, Weber, Martin S., Ochs, Jasmin, Bähr, Mathias, Doeppner, Thorsten R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901534/
https://www.ncbi.nlm.nih.gov/pubmed/33327747
http://dx.doi.org/10.1161/ATVBAHA.120.315031