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Macrolide Biosensor Optimization through Cellular Substrate Sequestration

[Image: see text] Developing and optimizing small-molecule biosensors is a central goal of synthetic biology. Here we incorporate additional cellular components to improve biosensor sensitivity by preventing target molecules from diffusing out of cells. We demonstrate that trapping erythromycin with...

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Detalles Bibliográficos
Autores principales: Miller, Corwin A., Ho, Joanne M., Parks, Sydney E., Bennett, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901672/
https://www.ncbi.nlm.nih.gov/pubmed/33555859
http://dx.doi.org/10.1021/acssynbio.0c00572