Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones

The work reported herein describes the synthesis of a new series of anti-inflammatory pyrazolyl thiazolones. In addition to COX-2/15-LOX inhibition, these hybrids exerted their anti-inflammatory actions through novel mechanisms. The most active compounds possessed COX-2 inhibitory activities compara...

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Detalles Bibliográficos
Autores principales: Elzahhar, Perihan A., Alaaeddine, Rana A., Nassra, Rasha, Ismail, Azza, Labib, Hala F., Temraz, Mohamed G., Belal, Ahmed S. F., El-Yazbi, Ahmed F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901699/
https://www.ncbi.nlm.nih.gov/pubmed/33618602
http://dx.doi.org/10.1080/14756366.2021.1887169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901699/
https://www.ncbi.nlm.nih.gov/pubmed/33618602
http://dx.doi.org/10.1080/14756366.2021.1887169

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