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Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF‐kB signaling pathways synergistically

OBJECTIVE: Differentiation‐inducing therapy for tumors is a strategy that aims to induce the differentiation and maturation of cancer stem cells (CSCs). The differentiation‐inducing capacity of arsenic trioxide (ATO) in hepatocellular carcinoma (HCC) and the underlying mechanism were previously unkn...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Hu, Bo, Sun, Yun‐Fan, Huang, Xiao‐Wu, Cheng, Jian‐Wen, Huang, Ao, Zeng, Hai‐Ying, Qiu, Shuang‐Jian, Cao, Ya, Fan, Jia, Zhou, Jian, Yang, Xin‐Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901720/
https://www.ncbi.nlm.nih.gov/pubmed/33634982
http://dx.doi.org/10.1002/ctm2.335