The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response

Dysregulation of collagen production and secretion contributes to aging and tissue fibrosis of major organs. How procollagen proteins in the endoplasmic reticulum (ER) route as specialized cargos for secretion remains to be fully elucidated. Here, we report that TMEM39, an ER-localized transmembrane...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Luo, Shuo, Barbosa, Guilherme Oliveira, Bai, Meirong, Kornberg, Thomas B., Ma, Dengke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901769/
https://www.ncbi.nlm.nih.gov/pubmed/33524011
http://dx.doi.org/10.1371/journal.pgen.1009317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901769/
https://www.ncbi.nlm.nih.gov/pubmed/33524011
http://dx.doi.org/10.1371/journal.pgen.1009317

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