The viral protein NSP1 acts as a ribosome gatekeeper for shutting down host translation and fostering SARS-CoV-2 translation

SARS-CoV-2 coronavirus is responsible for the Covid-19 pandemic. In the early phase of infection, the single-strand positive RNA genome is translated into nonstructural proteins (NSP). One of the first proteins produced during viral infection, NSP1, binds to the host ribosome and blocks the mRNA ent...

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Detalles Bibliográficos
Autores principales: Tidu, Antonin, Janvier, Aurélie, Schaeffer, Laure, Sosnowski, Piotr, Kuhn, Lauriane, Hammann, Philippe, Westhof, Eric, Eriani, Gilbert, Martin, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901841/
https://www.ncbi.nlm.nih.gov/pubmed/33268501
http://dx.doi.org/10.1261/rna.078121.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901841/
https://www.ncbi.nlm.nih.gov/pubmed/33268501
http://dx.doi.org/10.1261/rna.078121.120

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