ECT2 Increases the stability of EGFR and Tumorigenicity by Inhibiting Grb2 Ubiquitination in Pancreatic Cancer

The poor prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is associated with the invasion and metastasis of tumor cells. Epithelial cell transforming 2 (ECT2) is a guanine nucleotide exchange factor (GEF) of the Rho family of GTPases. It has also been reported that upregulation of...

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Detalles Bibliográficos
Autores principales: Wang, Junxiong, Yang, Shuo, Min, Li, Zhu, Shengtao, Guo, Shuilong, Zhang, Shutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901901/
https://www.ncbi.nlm.nih.gov/pubmed/33634019
http://dx.doi.org/10.3389/fonc.2020.589241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901901/
https://www.ncbi.nlm.nih.gov/pubmed/33634019
http://dx.doi.org/10.3389/fonc.2020.589241

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