The Expression of TRIM6 Activates the mTORC1 Pathway by Regulating the Ubiquitination of TSC1-TSC2 to Promote Renal Fibrosis

Renal fibrosis is considered as the final pathway of all types of kidney diseases, which can lead to the progressive loss of kidney functions and eventually renal failure. The mechanisms behind are diversified, in which the mammalian target of rapamycin (mTOR) pathway is one of the most important re...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Yi, Yang, Zhang, Chuanfu, Zhou, Baojuan, Liao, Lin, Liu, Wenrui, Hu, Jing, Xu, Qiming, Chen, Jie, Lu, Jianrao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901959/
https://www.ncbi.nlm.nih.gov/pubmed/33634104
http://dx.doi.org/10.3389/fcell.2020.616747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901959/
https://www.ncbi.nlm.nih.gov/pubmed/33634104
http://dx.doi.org/10.3389/fcell.2020.616747

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