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Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions

The anti-viral immune response is dependent on the ability of infected cells to sense foreign nucleic acids. In multiple species, the pattern recognition receptor (PRR) cyclic GMP-AMP synthase (cGAS) senses viral DNA as an essential component of the innate response. cGAS initiates a range of signali...

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Detalles Bibliográficos
Autores principales: Oliveira, Marisa, Rodrigues, Damaris Ribeiro, Guillory, Vanaique, Kut, Emmanuel, Giotis, Efstathios S., Skinner, Michael A., Guabiraba, Rodrigo, Bryant, Clare E., Ferguson, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901977/
https://www.ncbi.nlm.nih.gov/pubmed/33633733
http://dx.doi.org/10.3389/fimmu.2020.613079