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Chicken cGAS Senses Fowlpox Virus Infection and Regulates Macrophage Effector Functions
The anti-viral immune response is dependent on the ability of infected cells to sense foreign nucleic acids. In multiple species, the pattern recognition receptor (PRR) cyclic GMP-AMP synthase (cGAS) senses viral DNA as an essential component of the innate response. cGAS initiates a range of signali...
Autores principales: | Oliveira, Marisa, Rodrigues, Damaris Ribeiro, Guillory, Vanaique, Kut, Emmanuel, Giotis, Efstathios S., Skinner, Michael A., Guabiraba, Rodrigo, Bryant, Clare E., Ferguson, Brian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901977/ https://www.ncbi.nlm.nih.gov/pubmed/33633733 http://dx.doi.org/10.3389/fimmu.2020.613079 |
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