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Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line

Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including idiopathic pulmonary fibrosis (IPF). It has been postulated that paracrine mediators originating from senescent alveolar epithelia signal to surrounding mesenchymal cells and con...

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Detalles Bibliográficos
Autores principales: Sullivan, Daniel I., Jiang, Mao, Hinchie, Angela M., Roth, Mark G., Bahudhanapati, Harinath, Nouraie, Mehdi, Liu, Jie, McDyer, John F., Mallampalli, Rama K., Zhang, Yingze, Kass, Daniel J., Finkel, Toren, Alder, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902064/
https://www.ncbi.nlm.nih.gov/pubmed/33634147
http://dx.doi.org/10.3389/fmed.2021.600626