Cargando…
Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line
Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including idiopathic pulmonary fibrosis (IPF). It has been postulated that paracrine mediators originating from senescent alveolar epithelia signal to surrounding mesenchymal cells and con...
Autores principales: | Sullivan, Daniel I., Jiang, Mao, Hinchie, Angela M., Roth, Mark G., Bahudhanapati, Harinath, Nouraie, Mehdi, Liu, Jie, McDyer, John F., Mallampalli, Rama K., Zhang, Yingze, Kass, Daniel J., Finkel, Toren, Alder, Jonathan K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902064/ https://www.ncbi.nlm.nih.gov/pubmed/33634147 http://dx.doi.org/10.3389/fmed.2021.600626 |
Ejemplares similares
-
Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis
por: Sutton, Rachel M., et al.
Publicado: (2022) -
Intact mitochondrial function in the setting of telomere‐induced senescence
por: Sullivan, Daniel I., et al.
Publicado: (2023) -
Integrating the Integrated Stress Response
por: Bahudhanapati, Harinath, et al.
Publicado: (2022) -
The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease
por: Chen, Ting‐Yun, et al.
Publicado: (2020) -
GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis
por: Zhang, Yingze, et al.
Publicado: (2019)