EGFR-specific single-chain variable fragment antibody-conjugated Fe(3)O(4)/Au nanoparticles as an active MRI contrast agent for NSCLC

Overexpression of epidermal growth factor receptor (EGFR) is closely associated with a poor prognosis in non-small cell lung cancer (NSCLC), thus making it a promising biomarker for NSCLC diagnosis. Here, we conjugated a single-chain antibody (scFv) targeting EGFR with Fe(3)O(4)/Au nanoparticles to...

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Detalles Bibliográficos
Autores principales: Lu, Yuan, Huang, Jing, Li, Fakai, Wang, Yuan, Ding, Ming, Zhang, Jian, Yin, Hong, Zhang, Rui, Ren, Xinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902179/
https://www.ncbi.nlm.nih.gov/pubmed/33624188
http://dx.doi.org/10.1007/s10334-021-00916-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902179/
https://www.ncbi.nlm.nih.gov/pubmed/33624188
http://dx.doi.org/10.1007/s10334-021-00916-1

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