Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study

Papain-Like Protease (PLpro) is a key protein for SARS-CoV-2 viral replication which is the cause of the emerging COVID-19 pandemic. Targeting PLpro can suppress viral replication and provide treatment options for COVID-19. Due to the dynamic nature of its binding site loop, PLpro multiple conformat...

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Detalles Bibliográficos
Autores principales: Ismail, Muhammad I., Ragab, Hanan M., Bekhit, Adnan A., Ibrahim, Tamer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902231/
https://www.ncbi.nlm.nih.gov/pubmed/33662683
http://dx.doi.org/10.1016/j.compbiomed.2021.104295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902231/
https://www.ncbi.nlm.nih.gov/pubmed/33662683
http://dx.doi.org/10.1016/j.compbiomed.2021.104295

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