Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters

Adeno-associated viral vectors are widely used as vehicles for gene transfer to the nervous system. The promoter and viral vector serotype are two key factors that determine the expression dynamics of the transgene. A previous comparative study has demonstrated that AAV1 displays efficient transduct...

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Detalles Bibliográficos
Autores principales: Nieuwenhuis, Bart, Haenzi, Barbara, Hilton, Sam, Carnicer-Lombarte, Alejandro, Hobo, Barbara, Verhaagen, Joost, Fawcett, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902269/
https://www.ncbi.nlm.nih.gov/pubmed/32576975
http://dx.doi.org/10.1038/s41434-020-0169-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902269/
https://www.ncbi.nlm.nih.gov/pubmed/32576975
http://dx.doi.org/10.1038/s41434-020-0169-1

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