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Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters
Adeno-associated viral vectors are widely used as vehicles for gene transfer to the nervous system. The promoter and viral vector serotype are two key factors that determine the expression dynamics of the transgene. A previous comparative study has demonstrated that AAV1 displays efficient transduct...
Autores principales: | Nieuwenhuis, Bart, Haenzi, Barbara, Hilton, Sam, Carnicer-Lombarte, Alejandro, Hobo, Barbara, Verhaagen, Joost, Fawcett, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902269/ https://www.ncbi.nlm.nih.gov/pubmed/32576975 http://dx.doi.org/10.1038/s41434-020-0169-1 |
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