D1R- and D2R-Medium-Sized Spiny Neurons Diversity: Insights Into Striatal Vulnerability to Huntington’s Disease Mutation

Huntington’s disease (HD) is a devastating neurodegenerative disorder caused by an aberrant expansion of the CAG tract within the exon 1 of the HD gene, HTT. HD progressively impairs motor and cognitive capabilities, leading to a total loss of autonomy and ultimate death. Currently, no cure or effec...

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Detalles Bibliográficos
Autores principales: Bergonzoni, Guendalina, Döring, Jessica, Biagioli, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902492/
https://www.ncbi.nlm.nih.gov/pubmed/33642998
http://dx.doi.org/10.3389/fncel.2021.628010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902492/
https://www.ncbi.nlm.nih.gov/pubmed/33642998
http://dx.doi.org/10.3389/fncel.2021.628010

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