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FGFR-gerichtete Therapie von Kopf-Hals-Karzinomen
BACKGROUND: Genomic aberrations (mutations, gene fusions, amplifications) and dysregulation of the fibroblast growth factor (FGF) receptor (FGFR) signaling pathway are frequently found in squamous cell carcinomas of the head and neck (HNSCCs). Targeted therapy with tyrosine kinase inhibitors (TKIs)...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Medizin
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7902560/ https://www.ncbi.nlm.nih.gov/pubmed/32519203 http://dx.doi.org/10.1007/s00106-020-00893-2 |